Applications
Fibryn PRFM for Non-Healing Ulcers
Non-healing ulcers are a major health problem worldwide and have great impact at personal, professional and social levels, with high cost in terms of human and material resources.
Fibryn PRFM offers a better therapeutic option for the treatment of non-healing and diabetic foot ulcers, as it is an easy and cost-effective method, and provides the necessary growth factors that enhance tissue healing. Fibryn PRFM also exerts antimicrobial activity against some bacteria of the skin, and that the presence of infection is reduced in Fibryn treated wounds.
Patients can achieve full healing in an average of 6 weeks of twice-weekly treatments, ie, in 12 treatments.
Fibryn PRFM for Dental applications
PRFM is widely used in oral and maxillofacial surgery. It has emerged as one of the promising regenerative materials in the field of periodontics. Platelets play a key role in wound healing and hence wound healing after periodontal treatment can be accelerated by the use of platelet concentrates. The wound healing process initiated by the formation of blood clot and after tissue injury in periodontal surgery causes adherence and aggregation of platelets favoring the formation of thrombin and fibrin.
Fibryn PRFM is an autologous leukocyte platelet rich fibrin matrix composed of a tetra molecular structure with cytokines, platelets and stem cell within it. It acts as a biodegradable scaffold and also as a vehicle in carrying cells involved in tissue regeneration. Fibryn PRFM promotes a sustained release of growth factors in a period between 1 and 4 weeks stimulating the environment for wound healing in a significant amount of time.
Fibryn PRFM can be applied in
- Stand alone therapies includes using the fibrin plug or membrane as a filler material in extraction socketsto prevent complications and to enhance socket healing
- Additive therapies involve addition or mixing to bone substitutes such as xenograft or biphasic calcium phosphate (BCP) to enhance the formation of new bone
- Combination therapies where it can be used in combination with other biomaterials in bone augmentation and grafting sites as a graft material or barrier membrane.
